Sara De La Salle - 2016 to 2018
University of Ottawa

"Can Changes in Brain Activity Predict Who Will Respond to Ketamine as a Rapid Treatment for Depression?"

Most antidepressant medications take many weeks to become effective and don't always work for every patient. In fact, around 40% of people with major depressive disorder don't respond to current medications and are considered to be “treatment-resistant.” Recent studies have shown that a single low dose of the anesthetic drug ketamine can greatly reduce depression symptoms (depressed mood, guilt, work and interests, anxiety) and can diminish suicidal thoughts within hours of taking the medication.